Proven worldwide
Deployed across five continents
Designed and manufactured in the U.S.
90% customer reorder rate
20+ years of serving biopharma, pharmaceutical manufacturers, and CDMOs
Operational reliability

Advanced Cryogenic Freezing & Ultra-Low Temperature Freezers
Cryometrix designs and manufactures advanced liquid nitrogen (LN2)-powered freezing and cooling systems for biopharmaceutical manufacturing, blood banking, cell therapy, pharmaceutical processing, laboratory research, transportation logistics, and industrial low-temperature applications.
Our ultra-low temperature freezers are engineered to deliver faster freezing, rapid thermal recovery, improved temperature uniformity, and reduced maintenance compared with traditional compressor-based refrigeration systems. By using contained LN2 cooling technology, Cryometrix helps facilities improve operational efficiency while maintaining dependable
performance in demanding environments.
From blast freezing and plate freezing to cryogenic storage, transportation freezers, and ethanol chilling, Cryometrix provides scalable low-temperature solutions optimized for critical workflows where precision, reliability, and throughput matter.
Blast Freezing

Cryometrix blast freezers use advanced LN2 cooling technology to deliver ultra-fast freezing, precise temperature control, and rapid recovery performance for biologics manufacturing, plasma processing, blood banking, and laboratory workflows.
Unlike traditional mechanical refrigeration systems, Cryometrix blast freezers achieve rapid pull-down temperatures while reducing maintenance complexity, lowering facility heat output, and supporting consistent freezing performance during continuous operation.
Our blast freezing portfolio includes production-scale systems, compact laboratory platforms, and hybrid blast plate freezing technology designed for regulated and high-throughput environments. Our Blast Freezers include the B-90 Blast/Thaw Freezer, the MB-90 Blast/Thaw Freezer, and the new PF-90 Blast Plate Freezer.
Benefits of Cryometrix Blast Freezing
- Rapid ultra-low temperature pull-down
- Faster recovery after door openings
- Improved temperature uniformity
- Reduced process bottlenecks
- Compressor-free LN2 cooling
- Lower maintenance requirements
- Reduced HVAC load
- Scalable freezing performance
Applications
- Blood plasma freezing
- Biologics manufacturing
- Cell and gene therapy
- Pharmaceutical processing
- Research laboratories
- Bioprocess intermediates
Cryometrix blast freezers help organizations improve throughput, maintain product integrity, and support repeatable freezing workflows across critical operations.

Blast Plate Freezing
Cryometrix plate freezers combine conductive plate freezing technology and LN2-powered air-cooling to deliver highly uniform freezing for bagged biologics, plasma products, pharmaceutical materials, and sensitive research applications.
The PF-90 Blast Plate Freezer integrates both blast air circulated freezing and conductive plate freezing into a single platform, allowing facilities to support multiple freezing workflows with one advanced cryogenic system.
Conductive plate freezing removes heat through direct contact between the product and cold plates, improving freezing consistency and reducing thermal variability across bagged materials. See our new PF-90 Blast Plate Freezer.

Advantages of Plate Freezing
- Uniform conductive heat transfer
- Improved freezing consistency
- Reduced Cryoconcentration
- Reduced ice crystal formation
- Enhanced process repeatability
- Efficient freezing for bagged products
- Rapid ultra-low temperature performance
- Reduced maintenance complexity
- Flexible hybrid freezing capability
Applications
- Blood banking
- Plasma freezing
- Biopharmaceutical manufacturing
- Cell therapy workflows
- Pharmaceutical bag freezing
- Research and clinical laboratories
Cryometrix plate freezing systems are engineered for organizations requiring precise temperature control, repeatable freezing profiles, and reliable ultra-low temperature operation.


Ultra-Low Temperature Storage Freezers
Cryometrix ultra-low temperature storage freezers provide dependable long-term cryogenic preservation for biologics, vaccines, plasma, stem cells, pharmaceutical materials, and laboratory samples.
Using contained LN2 cooling technology, Cryometrix storage freezers eliminate compressor- driven refrigeration while improving temperature recovery, reducing maintenance requirements, and lowering electrical demand.
Our storage freezer portfolio supports applications ranging from standard ultra-low temperature storage to advanced cryogenic preservation below -135°C. Our Storage Freezers include the T-90 Storage Freezer, the T-135 Ultra-Low Freezer, and the MC-140 Chest Freezer.

Storage Freezer Benefits
- Temperatures down to -140°C
- Stable chamber temperature uniformity
- Fast thermal recovery
- Reduced electrical consumption
- Compressor-free cooling architecture
- Quiet operation
- Reduced maintenance requirements
- Reliable long-term preservation
Applications
- Biobanking
- Cell and gene therapy
- Blood and plasma storage
- Pharmaceutical preservation
- Biologics manufacturing
- Research laboratories

Ethanol & Alcohol Chillers
Cryometrix ethanol chillers are engineered for cannabis extraction, hemp processing, winterization, pharmaceutical solvent cooling, and industrial low-temperature applications.
Using advanced LN2-powered cooling technology, Cryometrix ethanol chillers deliver rapid pull- down performance and stable ultra-low temperatures down to -80°C while reducing facility heat load, maintenance demands, and electrical consumption.
Our chilling systems help extraction facilities improve process consistency, increase throughput, and maintain dependable solvent temperatures during demanding production workflows. Our Ethanol & Alcohol Chillers include the L-80 Lite Chiller, and the L-80 Max Chiller.

Ethanol Chilling Benefits
- Rapid ethanol cooling performance
- Temperatures down to -80°C
- Faster winterization workflows
- Improved extraction consistency
- Reduced HVAC demand
- Lower maintenance requirements
- Stable solvent temperature control
- Scalable extraction support
Applications
- Cannabis extraction
- Hemp processing
- Winterization
- Botanical extraction
- Pharmaceutical solvent cooling
- Industrial alcohol cooling
Cryometrix ethanol chillers help facilities improve operational efficiency while supporting repeatable low-temperature extraction processes.
Transportation Storage & Cold Chain Systems
Cryometrix transportation freezers and cold chain storage systems help protect pharmaceuticals, biologics, vaccines, and laboratory materials during shipping and logistics operations.
Our LN2-powered transportation freezers provide stable ultra-low temperature performance without relying on traditional compressor refrigeration or dry ice handling. Designed for autonomous operation and long-duration transport, Cryometrix transportation freezers support reliable cold chain protection across regional and global logistics network. See our S-90 Shipper Freezer and our RMF-90 Freight Freezer.

Transportation Freezer Benefits
- Autonomous cold chain operation
- Stable ultra-low temperature performance
- Extended hold times
- Reduced dry ice dependence
- Integrated monitoring and data logging
- Reliable pharmaceutical transportation
- Reduced maintenance complexity
- Flexible transportation configurations

Applications
- Vaccine transportation
- Pharmaceutical shipping
- Cell and gene therapy logistics
- Clinical trial distribution
- Laboratory sample transport
- Biologic and biospecimen shipping

Cryometrix transportation freezers help organizations maintain product integrity, reduce transportation risk, and improve cold chain reliability for critical materials.


Why Cryometrix?
Cryometrix systems are engineered to overcome the limitations of traditional mechanical refrigeration through advanced liquid nitrogen cooling technology.
Our compressor-free cryogenic systems provide rapid freezing and chilling performance whilere ducing operational complexity, minimizing maintenance requirements, and improving temperature consistency across critical workflows.
Cryometrix Advantages
- Faster ultra-low temperature performance
- Reduced maintenance and downtime
- Improved temperature uniformity
- Compressor-free cooling systems
- Lower electrical demand
- Reduced facility heat output
- Rapid recovery performance
- Scalable cryogenic solutions
- Designed for GMP and regulated environment
From blast freezing and cryogenic storage to transportation and solvent chilling, Cryometrix delivers advanced ultra-low temperature solutions engineered for demanding industrial, pharmaceutical, and research applications.

Industries We Serve
Cryometrix supports organizations operating in highly regulated and temperature-sensitive industries, including:
- Biopharmaceutical manufacturing
- Blood banking and plasma processing
- Cell and gene therapy
- Vaccine manufacturing and distribution
- Pharmaceutical processing
- Research laboratories
- Biobanking
- Clinical research
- Cannabis and hemp extraction
- Industrial low-temperature processing
Our systems are designed to help organizations improve throughput, maintain product quality, and support dependable ultra-low temperature workflows across critical operations.

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PF-90 Blast Plate Freezer








