Cryometrix S-90 Low Temperature Shipper
Advanced LN2-Based Cold Chain Shipping for Pharmaceuticals and Biotech
The Cryometrix S-90 Low Temperature Shipper is a state-of-the-art, ultra-low temperature shipping solution designed to meet the strict demands of pharmaceutical, biotechnology, clinical research, and cell therapy industries. By integrating a programmable temperature range, on-board liquid nitrogen (LN2) supply, and autonomous power source, the S-90 delivers unmatched reliability, safety, and operational efficiency for temperature-sensitive logistics.
Dry ice is rapidly becoming obsolete in high-value shipping due to its environmental impact, manual labor requirements, and lack of precise temperature control. The Cryometrix S-90 addresses these issues with cutting-edge LN2 freezing technology and eliminates the need for manual temperature stabilization, reducing both labor and risk.

Redefining Cold Chain Shipping
The S-90 enables precise temperature management across a programmable range of +20°C to -90°C, ensuring product stability across the entire shipping process. It holds payload temperatures with a uniformity of ±3°C, safeguarding biologics, vaccines, clinical trial materials, and other sensitive pharmaceutical products.
Unlike traditional shipping containers that rely on dry ice or mechanical cooling, the Cryometrix S-90 offers programmable, repeatable performance with digital control and logging. This ensures full compliance with Good Distribution Practice (GDP) and other regulatory standards.


Redefining Cold Chain Shipping
The S-90 enables precise temperature management across a programmable range of +20°C to -90°C, ensuring product stability across the entire shipping process. It holds payload temperatures with a uniformity of ±3°C, safeguarding biologics, vaccines, clinical trial materials, and other sensitive pharmaceutical products.
Unlike traditional shipping containers that rely on dry ice or mechanical cooling, the Cryometrix S-90 offers programmable, repeatable performance with digital control and logging. This ensures full compliance with Good Distribution Practice (GDP) and other regulatory standards.
Key Advantages of the Cryometrix S-90


Precise and Programmable Temperature Control
Maintaining an accurate temperature is critical in biopharmaceutical logistics. The S-90 allows users to set and maintain any temperature between +20°C and -90°C, eliminating the wide fluctuations commonly experienced with dry ice and conventional systems. This precision ensures the integrity of vaccines, biologics, and cell therapies throughout the entire supply chain.
The system also reaches -80°C in under 60 minutes, allowing for rapid deployment and minimizing preconditioning time.

Self-Contained System for True Portability
The S-90 is fully self-contained, with its own on-board liquid nitrogen storage tank and battery-powered electrical system. This independence from external power and cryogenic sources makes it ideal for both long-distance transportation and local distribution.
It can maintain a setpoint of -80°C for up to 15 days without refueling or recharging, providing assurance for long-haul shipments or customs delays.

Enhanced Data Integrity and Security
Cryometrix incorporates built-in temperature and user activity data logging that tracks freezer performance, alarms, and all user interactions. These logs are accessible via a touchscreen interface or can be downloaded via USB for compliance reporting, audits, or archiving.
The system supports up to 30 individual user profiles and three security levels, controlling who can access, adjust, or modify key operational settings. This ensures that only authorized personnel can open the unit, adjust the temperature setpoint, or configure system parameters.


High-Capacity Storage with Customizable Interior
The S-90 supports an interior volume of 33.5 cubic feet (or 950 liters) and can hold up to 72,000 cryogenic vials (1.2–2.0 mL, internally threaded). It includes adjustable shelving configured every 0.5 inches for maximum flexibility.
Standard configuration includes three stainless steel shelves, each capable of holding 6 racks with 5 boxes deep, based on a standard 100-vial box layout. This modular setup makes loading and unloading highly efficient, mimicking upright lab freezer functionality.

Specifications at a Glance
Property | Metric | Imperial |
---|---|---|
External Dimensions | 2438 x 1224 x 2387 mm | 96 x 48 x 94 in |
Internal Payload Volume | 950 L | 33.5 ft3 |
Payload Dimensions | 711 x 876 x 1524 mm | 28 x 34.5 x 60 in |
Weight | 4.2 cu ft / 120 L | 2500 lbs |
Power Requirements | 208–240 VAC | 120 VAC, 60 Hz |
LN2 Inlet Pressure | 1.5 Bar | 22 PSI |
Temperature Uniformity | ±3°C at -80°C | ±5°F at -130°F |
Ramp Rate | -1°C to -3°C/min | -2°F to -5°F/min |

Environmental Sustainability and Operational Efficiency
Reduced Energy Consumption
The S-90 uses up to 90 percent less energy than comparable mechanical compressor-based freezers. This drastic reduction in power demand is achieved by eliminating compressors and refrigerants entirely and utilizing the boiling point of LN2 (-196°C) as the primary cooling source.
This also enables silent operation, reducing noise pollution in lab and warehouse environments. Since LN2 requires no electricity to function, the unit can continue to operate effectively during power outages or natural disasters.
Sustainable Materials and Low Emissions
Constructed entirely of 100 percent stainless steel, both inside and out, the S-90 is built for longevity and easy sterilization. There are no refrigerant chemicals, oils, or CFCs involved, which makes the system environmentally friendly and regulatory compliant.
The only emission from the system is nitrogen, a harmless, inert gas that constitutes more than 75 percent of Earth’s atmosphere.

Extreme Reliability for Long-Term Investment
Fewer Moving Parts, Less Maintenance
Traditional compressor-based freezers contain numerous moving parts that wear over time and require regular maintenance. The S-90, by contrast, has virtually no moving components, which significantly extends its operational life and reduces maintenance costs.
This system design also enables operation across a wide range of ambient temperatures without the need for auxiliary HVAC systems.

Long Warranty and Support
Every Cryometrix S-90 comes with a 20-year warranty on the cooling system, a testament to its durability and performance. This extended warranty helps reduce total cost of ownership and provides long-term peace of mind for high-throughput laboratories, pharmaceutical manufacturers, and logistics providers.This system design also enables operation across a wide range of ambient temperatures without the need for auxiliary HVAC systems.

Why Choose the Cryometrix S-90?
The compact footprint of the S-90 (under 8 square feet) allows it to be easily integrated into any laboratory, distribution center, or production facility without major space or electrical infrastructure changes.
Because it requires no HVAC support and operates independently of local power, the S-90 is ideal for modular expansion, allowing organizations to scale cold storage capacity rapidly as needs grow.


Flexible Integration for Multiple Applications
The compact footprint of the S-90 (under 8 square feet) allows it to be easily integrated into any laboratory, distribution center, or production facility without major space or electrical infrastructure changes.
Because it requires no HVAC support and operates independently of local power, the S-90 is ideal for modular expansion, allowing organizations to scale cold storage capacity rapidly as needs grow.

Use Case Scenarios
The Cryometrix S-90 is designed for a wide range of life science and healthcare applications, including: This system design also enables operation across a wide range of ambient temperatures without the need for auxiliary HVAC systems.

Clinical Trials: Transporting temperature-sensitive patient samples or investigational drugs

Cell and Gene Therapy: Shipping of cryopreserved cells or genetically modified material

Vaccines and Biologics: Long-range shipment of cold chain biologics requiring exact temperature control

Academic and Government Labs: Centralized and distributed cold chain storage in high-security settings

Global Logistics Providers: Integration into pharmaceutical distribution networks with minimal energy and support costs

Why Choose Cryometrix S-90 Over Traditional Shippers?
Unlike dry ice-based or compressor-cooled containers, the Cryometrix S-90 offers:
- True programmability with digital temperature control
- Up to 15 days of autonomous power and cooling
- Massive capacity, reducing shipment frequency and cost
- Closed system architecture, ensuring no LN2 exposure to product or personnel
- Full traceability with built-in logs and user access management
- High energy efficiency, making it ideal for sustainability initiatives
Elevate Your Cold Chain Strategy with the Cryometrix S-90
The Cryometrix S-90 Low Temperature Shipper is a next-generation solution for organizations seeking to modernize and future-proof their cold chain shipping. With its innovative design, operational flexibility, and focus on sample integrity, the S-90 stands out as a smart investment for biopharma, research, and clinical sectors.
