BLAST FREEZERS
CRYOMETRIX PF-90
BLAST/THAW FREEZER
CRYOMETRIX B-90
BLAST/THAW FREEZER
CRYOMETRIX MB-90
BLAST/THAW FREEZER
Cryometrix Blast Freezers
Cryometrix offers a complete portfolio of LN2 blast freezers and blast plate freezers engineered for ultra-fast freezing, precise temperature control, and scalable performance in life science, biopharmaceutical, and research environments.
Unlike traditional compressor-based systems, Cryometrix freezers use liquid nitrogen (LN2)- cooled air in a contained system, enabling faster pull-down speeds, improved temperature uniformity, and reduced maintenance. This approach supports high-throughput workflows while minimizing downtime and operational complexity.
From compact lab-scale units to production-scale systems and hybrid technologies, Cryometrix provides solutions optimized for blast freezing, thawing, and advanced plate freezing applications.
Cryometrix B-90 Blast/Thaw Freezer
The Cryometrix B-90 blast freezer is a high-capacity, production-scale system designed for high-throughput blast freezing and thawing in demanding environments such as biopharmaceutical manufacturing, blood banks, and large research facilities.
Using LN2-based cooling, the B-90 achieves rapid temperature pull-down from ambient to -90°C in about 10 minutes and any temperature in between. Fast temperature setpoint recovery is also possible after door openings to maintain consistent cycle performance.
Features and benefits:
- Ultra-fast blast freezing for increased throughput and reduced bottlenecks
- Large capacity (~700 L / 26 cu ft) for bulk processing
- Dual freeze and thaw capability from +40°C to -90°C
- ±3°C temperature uniformity across the payload area
- Compressor-free LN2 design for lower maintenance and higher reliability
- Minimal heat output to reduce HVAC load and energy costs
- Integrated data logging and optional 21 CFR Part 11 compliance
The B-90 is ideal for operations requiring consistent, repeatable freezing at scale, especially in blood banking, plasma processing, and biologics manufacturing. Its integrated data logging, user controls, and optional regulatory compliance features make it suitable for GMP and FDA- regulated environments.
Cryometrix MB-90 Blast/Thaw Freezer
The Cryometrix MB-90 blast freezer is a compact, high-performance solution designed for laboratories, process development, and smaller-scale bioprocessing environments.
Despite its size, the MB-90 delivers industry-leading performance, achieving ambient-to -90°C in as little as 3 minutes. This rapid freezing capability helps reduce ice crystal formation and preserve sensitive materials such as cell therapies, viral vectors, and biologics.
Features and benefits:
- 3-minute ultra-fast pull-down and approximately 1-minute recovery
- Compact footprint (under 8 square feet) for space-constrained labs
- Up to 90% lower energy consumption compared with mechanical freezers
- Flexible temperature range from +40°C to -90°C
- Low-maintenance LN2 cooling system with no compressors
The MB-90 is well suited for R&D, clinical workflows, and scale-down modeling. It shares core technology with the B-90, allowing processes developed at lab scale to transfer efficiently into production environments.
Cryometrix PF-90 Blast Plate Freezer
The Cryometrix PF-90 blast plate freezer combines LN2 blast freezing and plate freezing in a single system, delivering both speed and precision for applications where uniform freezing and product consistency are critical.
Facilities have traditionally needed separate systems for blast freezing and plate freezing. The PF-90 removes that limitation by integrating both methods into one platform, allowing operators to choose the most effective approach for each process.
Features and benefits:
- Dual freezing capability with both air blast and conductive plate freezing
- LN2-powered cooling for rapid pull-down and consistent ultra-low temperatures
- No refrigerant circulation within plates, reducing complexity and maintenance
- Improved uniformity for bagged products through direct contact heat transfer
- Reduced ice crystal formation to help maintain product integrity
- Flexible operation for mixed loads and standardized bag formats
Plate freezing uses direct contact between cold plates and the product to deliver controlled, consistent heat removal. This method is especially effective for biologics and blood products stored in bags, where uniform freezing profiles are important for maintaining quality and reproducibility.
Blast freezing remains essential for workflows that involve mixed loads, irregular containers, or high-speed processing. By combining both approaches, the PF-90 allows facilities to adapt to a wider range of applications without compromising performance.
The PF-90 is designed for:
Biopharmaceutical manufacturing and biologics processing
Blood banking and
plasma freezing
Cell and gene therapy
applications
Research and clinical laboratories requiring repeatable freezing
It is optimized for bagged materials commonly used in pharmaceutical workflows and can support multiple containers per cycle, with customization available for different formats.
By integrating both freezing methods into one system, the PF-90 helps reduce equipment redundancy, simplify workflows, and improve overall efficiency while maintaining strict control over freezing conditions.
Choosing the Right Cryometrix Freezer
Cryometrix systems are designed to support different operational needs:
B-90
for high-capacity, production-scale blast freezing
MB-90
for compact, fast-cycle lab
and development work
PF-90
for combined blast and plate freezing where precision and flexibility are required
Together, these solutions help optimize freezing performance, improve product quality, and support efficient workflows across research, clinical, and manufacturing environments.